MicroRNA let-7b-regulated epidermal stem cell proliferation in hypertrophied anal papillae

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MicroRNA let-7b-regulated epidermal stem cell proliferation in hypertrophied anal papillae

The present study investigated the role of epidermal stem cell-expressed microRNA let-7b in the pathogenesis of hypertrophied anal papillae. Hypertrophied anal papillae were examined for the presence of epidermal stem cells. Epidermal stem cells were identified using flow cytometry and immunofluorescent staining for the cell surface markers, integrin α6 and integrin β1 subunits. Expression leve...

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Hypertrophied anal papillae and fibrous anal polyps, should they be removed during anal fissure surgery?

AIM Hypertrophied anal papillae and fibrous anal polyps are not given due importance in the proctology practice. They are mostly ignored being considered as normal structures. The present study was aimed to demonstrate that hypertrophied anal papillae and fibrous anal polyps could cause symptoms to the patients and that they should be removed in treatment of patients with chronic fissure in anu...

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Removal of hypertrophied anal papillae and fibrous polyps improves outcome of anal fissure surgery

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ژورنال

عنوان ژورنال: Molecular Medicine Reports

سال: 2015

ISSN: 1791-2997,1791-3004

DOI: 10.3892/mmr.2015.4017